"Set five years after the cataclysmic events of Thanos's victory, half of the universe's sentient life is gone, and the completed Infinity Gauntlet has disappeared with the Mad Titan to a faraway world. However, even in this seemingly hopeless situation, the surviving heroes of the universe (Avengers, Guardians, and anyone else who is brave enough to fight on) are left to pick up the pieces. With a bit of hope, they intend to revive their friends and allies and the untold trillions of living beings that Thanos killed, and find a way to defeat him once and for all. But it won't be easy, and devastating sacrifices will have to be made in order to restore reality to a normal state."
It's all been leading to this. Originally coming out May 3, 2019, it's been moved up to April 26.