When I play an MMORPG, I almost, for sure, choose a female character. They are treated much better on these games by guys who are desperate for girls and I appreciate the extra help, and maybe trolling a little bit! Plus, i'd rather stare at a girl's ass for hours on ends than a guy's. When it comes to single player games, it depends on the art style, and the different choices, stats, and class choices. I don't think there is anything wrong with playing a character of the opposite gender, and I personally prefer it sometimes.